张韵佳（zhangyunjia@genomics.cn），北京华大生命科学研究院副研究员。中国科学院生物物理研究所神经生物学博士，毕业后在UTSW做博后5年，研究方向是体内及体外神经再生、胶质细胞重编程。2021年底加入华大，主要研究方向为脑发育、脑功能和脑疾病、单细胞组学、时空组学。 累计发表SCI论文4篇。
研究方向：单细胞组学、时空组学等方法研究脑发育、脑功能和脑疾病
现任岗位：华大研究院 北京分院 北京科研合作中心 生物信息副研究员
教育背景：中国科学院大学 神经生物 博士
参与项目：
1.人胎脑发育
2.胎儿脑干发育
3.小鼠视觉系统主要脑区时空转录组
论文：
1.Yunjia Zhang*, Xunan Shen*, Youning Lin*, Xiaobo Shi, Tao Zhou, Zhenkun Zhuang, Chunqiong Li, Meng Li, Yaqi Li, Li Zhang, Songhai Shi, Shiping Liu, Yaoyao Zhang. Spatial-temporal transcriptomics of human fetal brain development. 2025.(Manuscript in preparation)
2.Yunjia Zhang, Boxun Li, Sergio Cananzi, Chuanhui Han, Lei-Lei Wang, Yuhua Zou, Yang-Xin Fu, Gary C Hon, Chun-Li Zhang. A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum. Proc Natl Acad Sci U S A. 2022.
3.Yunjia Zhang, Mengmeng Chen, Zilong Qiu, Keping Hu, Warren McGee, Xiaoping Chen, Jianghong Liu, Li Zhu*and Jane Y. Wu*. MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2. Proteinand Cell.2016.
4.Hong Ma, Yunjia Zhang, Hailong Wang, Chuanhui Han, Runhong Lei, Lei Zhang, Zuye Yang, Ling Rao, Hong Qing, Jianhua Xiang, Yulin Deng*. Effect and mechanism of Mitomycin C combined with recombinant adeno-associated virus type II against glioma. Int J Mol Sci. 2014. (共一作第二)
5.Chuanhui Han†, Zhida Liu†, Yunjia Zhang, Aijun Shen, Chunbo Dong, Anli Zhang, Casey Moore, Zhenhua Ren, Changzheng Lu, Xuezhi Cao, Chun-Li Zhang, Jian Qiao & Yang-Xin Fu.Tumor cells suppress radiation-induced immunity byhijacking caspase 9 signaling. Nature Immunology. 2020.
6.Tianyi Xia 1 2, Luni Hu 1 2, Lulu Zuo 3, Lei Cao 1 2,Yunjia Zhang 1 2, Mengyang Xu 2 4, Qin Lu 2, Lei Zhang 1 2, Taotao Pan 1 2, Bohan Zhang 1 2, Bowen Ma 1 2, Chuan Chen 1 2, Junfu Guo 3, Chang Shi 3, Mei Li 2, Chao Liu 5 6, Yuxiang Li 7 8 9, Yong Zhang 10 11 12, Shuangsang Fang. ST-GEARS: Advancing 3D downstream research through accurate spatial information recovery. Nat Commun. 2024.
7.Zuye Yang, Yunjia Zhang, Hailong Wang, Hong Ma, Yulin Deng*. Effect and Mechanism of Gamma Ray (Co60) on the Bioavailabilityof Recombinant Adeno-Associated Virus [A]. Chinese Space Science and SpaceSociety and the Professional Committee of the origin of life and evolution of lunar science and comparative planetary science professional committee, 2013, Annual Symposium[C].
