钟裕(zhongyu1@genomics.cn),香港中文大学博士,助理研究员,重庆高新区“金凤凰”青年人才。近五年内,在国际重要学术期刊发表论文18篇,其中以第一作者或共同第一作者在Cell,International Journal of Biological Sciences,Clinical and Translational Medicine等权威期刊发表论文9篇。申请发明专利2项,其中以第一发明人申请发明专利1项。
研究方向:基于细胞组学和时空组学的肿瘤研究及临床应用方向
现任岗位:华大研究院 西南分院 精准所 疾病图谱研究 生物信息副研究员
教育背景:香港中文大学 内科科学 博士
参与项目:
1.时空多组学解析肿瘤转移定植的动态微环境
2.早期复发肝癌微环境及逃逸机制研究
3.结直肠癌多区域免疫微环境单细胞图谱
4.基于多组学技术的肿瘤诊断
5.单细胞双维度表观组学技术开发及应用
论文:
1.Sun Y#, Wu L#*, Zhong Y#, et al. Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma. Cell. 2021 Jan 21;184(2):404-421.e16. (共同第一作者)
2.Zhong Y, Wei B, Wang W, Chen J, Wu W, Liang L, Huang XR, Szeto CC, Yu X, Nikolic-Paterson DJ, Lan HY*. Single-Cell RNA-Sequencing Identifies Bone Marrow-Derived Progenitor Cells as a Main Source of Extracellular Matrix-Producing Cells Across Multiple Organ-Based Fibrotic Diseases. Int J Biol Sci. 2024 Sep 16;20(13):5027-5042. (第一作者)
3.Wang C#, Huang W#, Zhong Y#, et al. Single-cell multi-modal chromatin profiles revealing epigenetic regulations of cells in hepatocellular carcinoma. Clin Transl Med. 2024 Sep;14(9):e70000. (共同第一作者)
4.Wang W#, Zhong Y#, Zhuang Z#, et al. Multiregion single-cell sequencing reveals the transcriptional landscape of the immune microenvironment of colorectal cancer. Clin Transl Med. 2021 Jan;11(1):e253. (共同第一作者)
5.Wang Z#, Zhong Y#, Zhang Z#, et al. Characteristics and Clinical Significance of T-Cell Receptor Repertoire in Hepatocellular Carcinoma. Front Immunol. 2022 Mar 16;13:847263. (共同第一作者)
6.Xiao G#, Huang W#, Zhong Y#, et al. Uncovering the Bronchoalveolar Single-Cell Landscape of Patients With Pulmonary Tuberculosis With Human Immunodeficiency Virus Type 1 Coinfection. J Infect Dis. 2024 Feb 27:jiae042. (共同第一作者)
7.Mu T#, Xu L#, Zhong Y#, et al. Embryonic liver developmental trajectory revealed by single-cell RNA sequencing in the Foxa2eGFP mouse. Commun Biol. 2020 Nov 3;3(1):642. (共同第一作者)
8.Zhang Y#, Zhou X#, Zhong Y#, et al. Hum Mol Genet. 2024 Feb 1;33(4):342-354. (共同第一作者)
9.Guo Q#, Zhong Y#, Wang Z# et al. Single-cell transcriptomic landscape identifies the expansion of peripheral blood monocytes as an indicator for HIV-1-TB coinfection. Cell Insight 1.1 (2022): 100005. (共同第一作者)
Google scholar个人主页地址:https://scholar.google.com.hk/citations?user=5let3nYAAAAJ&hl=zh-CN&oi=ao


