徐德敏(xudemin@genomics.cn),博士,生物技术副研究员。
研究方向:
1.基于“活字印刷”方式的DNA存储自动化写入研究
2.体内DNA存储的功能模块研究
现任岗位:华大研究院 北京分院 生化所 DNA存储 生物技术副研究员
教育背景:中国科学技术大学 遗传学 博士
参与项目:
1.基于标准库原理的DNA存储集成系统
2.基于单分子甲基化测序的DNA存储应用示范
3.DNA存储高时效纠错与解码方法
论文:
1.Xu D, Chen X, Kuang Y, Hong M, Xu T, Wang K, Huang X, Fu C, Ruan K, Zhu C, Feng X, Guang S. rRNA intermediates coordinate the formation of nucleolar vacuoles in C. elegans. Cell Rep. 2023.
2.Xu T, Liao S, Huang M, Zhu C, Huang X, Jin Q, Xu D, Fu C, Chen X, Feng X, Guang S. A ZTF-7/RPS-2 complex mediates the cold-warm response in C. elegans. PLoS Genet. 2023.
3.Liao S, Chen X, Xu T, Jin Q, Xu Z, Xu D, Zhou X, Zhu C, Guang S, Feng X. Antisense ribosomal siRNAs inhibit RNA polymerase I-directed transcription in C. elegans. Nucleic Acids Res.
4.Zeng C, Weng C, Wang X, Yan YH, Li WJ, Xu D, Hong M, Liao S, Dong MQ, Feng X, Xu C, Guang S. Functional proteomics Identifies a PICS complex required for piRNA maturation and chromosome segregation. Cell Rep. 2019.
5.Hong, M., Zhou, X., Zeng, C., Xu, D., Xu, T., Liao, S., ... & Guang, S. Nucleolar stress induces nucleolar stress body formation via the NOSR-1/NUMR-1 axis in Caenorhabditis elegans. Nature Communications, 2024.
6.Chen, X., Wang, K., Mufti, F. U. D., Xu, D., Zhu, C., Huang, X., ... & Guang, S. Germ granule compartments coordinate specialized small RNA production. Nature Communications, 2024.


