郝世杰(haoshijie@genomics.cn),博士,生物信息副研究员。长期从事动植物基因组学,细胞组学工具研发和细胞生物学研究,在时空单细胞脑图谱,衰老和再生细胞图谱等方面获得多项重要成果。共参与发表18篇SCI论文,相关成果发表于Science, Cell, Nature communications, Nature Genetics, GigaScience, Developmental cell等杂志,其中一作论文六篇。
研究方向:生物信息学
现任岗位:华大研究院 杭州分院 细胞所 生物信息副研究员
教育背景:中国科学院大学 基因组学 博士
参与项目:
1.“全脑介观神经联接图谱” 国际大科学计划(Mesoscopic Brain Connectome Project , MBCP)
论文:
1.Xu J#, Guo P#, Hao S#, Shangguan S#, Shi Q#, Volpe G#, Huang K, Zuo J, An J, Yuan Y, Cheng M, Deng Q, Zhang X, Lai G, Nan H, Wu B, Shentu X, Wu L, Wei X, Jiang Y, Huang X, Pan F, Song Y, Li R, Wang Z, Liu C, Liu S, Li Y, Yang T, Xu Z, Du W, Li L, Ahmed T, You K, Dai Z, Li L, Qin B, Li Y, Lai L, Qin D, Chen J, Fan R, Li Y, Hou J, Ott M, Sharma AD, Cantz T, Schambach A, Kristiansen K, Hutchins AP, Gottgens B, Maxwell PH, Hui L, Xu X, Liu L, Chen A, Lai Y and Esteban MA. A spatiotemporal atlas of mouse liver homeostasis and regeneration[J]. Nat Genetics, 2024 (Co-first author)
2.Wu B#, Shentu X#, Nan H#, Guo P#, Hao S#, Xu J, Shangguan S, Cui L, Cen J, Deng Q, Wu Y, Liu C, Song Y, Lin X, Wang Z, Yuan Y, Ma W, Li R, Li Y, Qian Q, Du W, Lai T, Yang T, Liu C, Ma X, Chen A, Xu X, Lai Y, Liu L, Esteban MA and Hui L. A spatiotemporal atlas of cholestatic injury and repair in mice[J]. Nat Genetics, 2024 (Co-first author)
3.Xu J#, Hao S#, Shi Q, Deng Q, Jiang Y, Guo P, Yuan Y, Shi X, Shangguan S, Zheng H, Lai G, Huang Y, Wang Y, Song Y, Liu Y, Wu L, Wang Z, Cheng J, Wei X,Cheng M, Lai Y, Volpe G, Esteban MA, Hou Y, Liu C and Liu L. Transcriptomic Profile of the Mouse Postnatal Liver Development by Single-Nucleus RNA Sequencing[J]. Frontiers in Cell and Developmental Biology, 2022, 10: 833392. (Co-first author)
4.Jiang Y#, Hao S#, Chen X, Cheng M, Xu J, Li C, Zheng H, Volpe G, Chen A, Liao S, Liu C*, Liu L* and Xu X*. Spatial Transcriptome Uncovers the Mouse Lung Architectures and Functions[J]. Frontiers in Genetics, 2022, 13: 858808. (Co-first author)
5.Hao S#, Han K#, Meng L, Huang X, Cao W, Shi C, Zhang M, Wang Y, Liu Q, Zhang Y, Sun H, Seim I, Xu X, Liu X* and Fan G*. African Arowana Genome Provides Insights on Ancient Teleost Evolution[J]. iScience, 2020, 23(11): 101662. (First author)
6.Hao S#, Ge Q#, Shao Y#, Tang B, Fan G, Qiu C, Wu X, Li L, Liu X, Shi C* and Lee SM*. Chromosomal-level genome of velvet bean (Mucuna pruriens) provides resources for L-DOPA synthetic research and development[J]. DNA Research, 2022, 29(5) (First author)


