仝欣(tongxin@genomics.cn),基因组学副研究员,毕业于湖南农业大学生物信息学专业,后深耕基因组学领域超过10年。主要的研究方向为人基因组重测序和宿主基因组与人体共生微生物的互作关系研究,发表论文10余篇(其中共同一作4篇),授权专利4项,曾获盐田区“高级人才”及盐田区“优秀共产党员”荣誉称号。
研究方向:基因组学、宏基因组学
现任岗位:华大研究院 华中分院 精准健康研究所 生物信息副研究员
教育背景:湖南农业大学 生物信息学 本科
参与项目:
1.宿主基因组和人体多部位宏基因组互作研究项目
2.结直肠癌的宏基因组研究项目
3.自闭症家系基因组研究项目
4.YH单倍型基因组研究项目
论文:
1.Liu X, Tong X, Zou L, et al. A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome[J]. Communications Biology, 2024, 7(1): 139.
2.Qin Y, Tong X, Mei W J, et al. Consistent signatures in the human gut microbiome of old-and young-onset colorectal cancer[J]. Nature Communications, 2024, 15(1): 3396.
3.Liu X, Tong X, Jie Z, et al. Sex differences in the oral microbiome, host traits, and their causal relationships[J]. iScience, 2023, 26(1).
4.Liu X, Tong X, Zou Y, et al. Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome[J]. Nature genetics, 2022, 54(1): 52-61.
5.Liu X, Tong X, Zhu J, et al. Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome[J]. Cell Discovery, 2021, 7(1): 1-16.
6.Zhu J, Tian L, Chen P, Han M,Song L,Tong X et al. Over 50,000 metagenomically assembled draft genomes for the human oral microbiome reveal new taxa[J]. Genomics, proteomics & bioinformatics, 2021.
7.Liu X, Tang S, Zhong H, Tong X et al. A genome-wide association study for gut metagenome in Chinese adults illuminates complex diseases[J]. Cell discovery, 2021, 7(1): 1-15.
8.Wang F, Huang S, Gao R,…,Tong X et al. Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility[J]. Cell discovery, 2020, 6(1): 1-16.
9.Yuen R K C, Merico D, Cao H, Giovanna P, Babak A, Bhooma T, Tong X et al. Genome-wide characteristics of de novo mutations in autism[J]. NPJ genomic medicine, 2016, 1(1): 1-10.
10.Cao H, Wu H, Luo R, Huang S,Sun Y,Tong X et al. De novo assembly of a haplotype-resolved human genome[J]. Nature biotechnology, 2015, 33(6): 617-622.


