杜晓（duxiao@genomics.cn），美国迈阿密大学海洋生物学博士，深圳华大生命科学研究院生物信息副研究员，主要研究方向为单细胞及时空组学、基因组学、海洋生物学。主要研究内容包括基于单细胞组学的发育演化研究、基于全基因组重测序的遗传多态性研究、群体进化研究等。相关研究成果发表于Nature、Nature Communications、Genomics, Proteomics & Bioinformatics等国际权威期刊，至今累计发表SCI论文17篇，其中第一作者及通讯作者8篇。
研究方向：博士期间即从事基因组学研究工作，在美国重点海洋基因组实验室任助理研究员7年，曾参与美国国家科学基金会（NSF）遗传机制研究项目，开展环境污染对群体遗传序列和功能分化的研究。目前主要利用单细胞及时空学技术，对关键进化节点的水生生物各发育阶段进行研究，聚焦对胚胎发育及物种器官演化的研究。
现任岗位：华大研究院 青岛分院 地球所 生物信息副研究员
教育背景：美国迈阿密大学 海洋生物与渔业 博士
参与项目：
1.南海长棘海星种群分布与扩散机制（项目：南海长棘海星灾害暴发机理、监测预警与防控技术研究，参与，国家级，2023.1-2026.12
论文:
1.Ruihua Zhang, Qun Liu, Shanshan Pan, Yingying Zhang, Yating Qin, Xiao Du, Zengbao Yuan, Yongrui Lu, Yue Song, Mengqi Zhang, Nannan Zhang, Jie Ma, Zhe Zhang, Xiaodong Jia, Kun Wang, Shunping He, Shanshan Liu, Ming Ni, Xin Liu, Xun Xu, Huanming Yang, Jian Wang, Inge Seim & Guangyi Fan. A single-cell atlas of West African lungfish respiratory system reveals evolutionary adaptations to terrestrialization. Nature Communications. 2023-09-13.
2.Varshney, R. K., Roorkiwal, M., Sun, S., Bajaj, P., Chitikineni, A., Thudi, M., Singh, N. P., Du, X., … Liu, X. (2021). A chickpea genetic variation map based on the sequencing of 3,366 genomes. Nature, 599(7886), 622–627.
3.Du, X. , Li, L. , Liang, F. , Liu, S. , & J Huang. (2021). Robust benchmark structural variant calls of an asian using the state-of-art long fragment sequencing technologies. Genomics, Proteomics & Bioinformatics.
4.Zhao, H. *, Sun, S. *, Ding, Y. *, Wang, Y. *, Yue, X., Du, X., Wei, Q., Fan, G., … Gao, Z. (2021). Analysis of 427 genomes reveals moso bamboo population structure and genetic basis of property traits. Nature Communications, 12(1), 5466.
5.Xu, M., Guo, L., Du, X., Li, L., Peters, B. A., Deng, L., Wang, O., Chen, F., Wang, J., Jiang, Z., Han, J., Ni, M., Yang, H., Xu, X., Liu, X., Huang, J., & Fan, G. (2021). Accurate Haplotype-Resolved Assembly Reveals The Origin Of Structural Variants For Human Trios. Bioinformatics. 2021 Feb 4:btab068.
6.Lu, S.*, Zhu, J.*; Du, X.*, Sun, S., Meng, L., Liu, S., Fan, G., et al. Genomic selection for resistance to Streptococcus agalactiae in GIFT strain of Oreochromis niloticus by GBLUP, wGBLUP, and BayesC π. Aquaculture 523, 735212, (2020).
7.Ruggeri, P., Du, X., Crawford, D. L. & Oleksiak, M. F.. Evolutionary Toxicogenomics of the Striped Killifish (Fundulus majalis) in the New Bedford Harbor (Massachusetts, USA). International journal of molecular sciences. 20, 5, (2019).
8.Dayan, D. I., Du, X., Baris, T. Z., Wagner, D. N., Crawford, D. L. & Oleksiak, M. F.. Population genomics of rapid evolution in natural populations: Polygenic selection in response to power station thermal effluents. BMC Evolutionary Biology. 19, 1, 61, (2019).
9.Wu, Y. *, Zhang, Y. *, Hou, Z. *, Fan G., Pi, J., Sun, S., Chen, J., Liu, H., Du, X. et al. Population genomic data reveal genes related to important traits of quai, Gigascience, 2018, 7(5): giy049.
10.Du, X., Crawford, D. L., Nacci, D. E. and Oleksiak, M. F.. Heritable oxidative phosphorylation differences in a pollutant resistant Fundulus heteroclitus population. Aquatic Toxicology 177: 44-50, (2016).
