戴玺(daixi@genomics.cn),博士毕业于中国科学院大学,杭州华大生命科学研究院生物信息副研究员,从事单细胞组学及时空组学数据分析工作,主要研究方向为食蟹猴百万单细胞染色质可及性图谱研究、灵长类早期胚胎发育的转录调控变化等。
研究方向:单细胞组学图谱研究、灵长类早期胚胎发育
现任岗位:华大研究院 超级细胞所 生物信息副研究员
教育背景:中国科学院大学 基因组学 博士
参与项目:
1.食蟹猴百万单细胞染色质可及性图谱研究
2.食蟹猴植入后胚胎发育的染色质开放性图谱
3.人类植入后胚胎发育的多组学研究
论文:
1.Dai X*, Shao H*, Sun N*, et al. Developmental dynamics of chromatin accessibility during post-implantation development of monkey embryos[J]. GigaScience, 2023, 12.
2.Zou X*, Dai X*, Mentis A F A, et al. From monkey single-cell atlases into a broader biomedical perspective[J]. Life Medicine, 2022, 1(3): 254-257.
3.Niu Y*, Sun N*, Li C*, …, Dai X, et al. Dissecting primate early post-implantation development using long-term in vitro embryo culture[J]. Science, 2019, 366.
4.Xiang L*, Yin Y*, Zheng Y*, …, Dai X, et al. A developmental landscape of 3D-cultured human pre-gastrulation embryos[J]. Nature, 2020, 577: 537-542.
5.Chen A*, Liao S*, Cheng M*, …, Dai X, et al. Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays[J]. Cell, 2022, 185: 1777-1792 e1721.
6.Liu C*, Wang M*, Wei X*, …, Dai X, et al. An ATAC-seq atlas of chromatin accessibility in mouse tissues[J]. Sci Data, 2019, 6: 65.
7.Li J*, Wang Q*, An Y, …, Dai X, et al. Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Mesenchymal Stem/Stromal Cells Derived from Human Placenta[J]. Front Cell Dev Biol, 2022, 10: 836887.
8.Wang Q*, Li J*, Wang S*, …, Dai X, et al. Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal-fetal interface[J]. Sci Rep, 2022, 12: 10892.
9.Wang Q*, Li J*, Wang S*, …, Dai X, et al. Single-cell transcriptome profiling reveals molecular heterogeneity in human umbilical cord tissue and culture-expanded mesenchymal stem cells[J]. FEBS J, 2021, 288: 5311-5330.
10.Feng W*, Liu S*, Deng Q*, ..., Dai X, et al. A scATAC-seq atlas of chromatin accessibility in axolotl brain regions[J]. Scientific Data, 2023, 10(1): 627.


