邹远强（zouyuanqiang@genomics.cn），丹麦哥本哈根大学分子生物医学博士，正高级研究员，深圳市人体微生物检测与干预工程实验室副主任，中国科学院大学华大教育中心研究生导师，郑州大学、大连理工大学、东北林业大学硕士/博士生导师。现为深圳华大生命科学研究院宏基因组学方向负责人，主要从事人体微生物培养组和基因组研究和益生菌的功能开发和产业转化。国内人体微生物培养组研究领域的开拓者，构建了迄今为止该领域最大的肠道菌株库和肠道参考基因组数据库，相关成果先后于2019年和2013年发表在国际顶级期刊Nature Biotechnology和Nature Communications上，并被评选为《2019年度中国生物信息学十大应用》和《2019年度中国生物信息学十大进展》。2021年，2023年，2024年相继被评为华大集团“优秀导师”。主持国自然科学基金项目2项，作为核心骨干参与10多项国家重点研发计划项目，广东省重点项目等省部级科研项目。主导多项益生菌的知识产权的产业转化，收益3000余万元。在国际顶级期刊《Nature Biotechnology》，《Nature Genetics》，《Nature Communications》，《iMeta》等发表论文或评论60篇，申请专利30余项。参与2项团队标准的制定。
研究方向：微生物学
现任岗位：华大研究院 精准所 生物技术副研究员
教育背景：哥本哈根大学 分子生物医学 博士
参与项目：
1.“胆汁酸介导的克里斯坦森氏菌对非酒精性脂肪肝的作用机理研究”——国自然面上项目，32570057，2026/01-2029/12、50万元、主持。
2.“靶向菌群改善人体代谢健康功能食品关键技术攻关”——深圳市重点专项，2024.12-2027.12，400万，在研，项目骨干。
3.“人体微生物与宿主互作的分子图谱研究及应用”——深圳市重点项目，2025.01-2028.12，200万，在研，项目骨干。
4.“短程胰岛素强化治疗逆转2型糖尿病的肠胰岛轴多组学机制探讨和干预研究”——广东省面上，2023-2025，10万，在研，项目骨干。
5.“深圳市人体肠道微生态检测与干预工程实验室提升”——深圳市发改委工程实验室，2021年-2025年，1400万元，在研，实验室副主任。
6.“基于比较基因组学探究人体肠道可培养优势菌Faecalibacterium prausnitzii的遗传多样性”——国自然青年基金，32100009，2022/01-2024/12、30万元、结项、主持。
论文:
1. Ningning He, Mengjie Mu, Xiaofang Li, Qingyuan Hao, Kaiwei Chen, Xinnan Zhao, Yang Sun, Haoyu Wang, Zhinan Wu, Hewei Liang, Mengmeng Wang, Liang Xiao, Tao Yu, Zhi-Peng Wang*, Jixing Peng*, Yuanqiang Zou*, Shangyong Li*. Gut commensal antibiotic-resistant Parabacteroides goldsteinii ameliorates mouse colitis through valine-isobutyrate metabolism. Research. 2025 11:8:0867. (通讯作者)
2. Zhuye Jie, Hewei Liang, Yanzheng Meng, Jiahao Zhang, Tao Zhang, Wenxi Li, Xiaoqian Lin, Tongyuan Hu, Mo Han, Weiting Liang, Yanmei Ju, Xin Tong, Xin Jin, Xun Xu, Wenwei Zhang, Jian Wang, Huanming Yang, Karsten Kristiansen*, Liang Xiao* & Yuanqiang Zou*. Integrating metagenomics and cultivation unveils oral phage diversity and potential impact on hosts. npj biofilms and microbiomes. 2025 11, 145. https://doi.org/10.1038/s41522-025-00773-z. (通讯作者)
3. Cong Yang, Jingxi Sun, Ling Li, Jin Zheng, Chuhan Wang, Yu Zhao, Duo Yun, , Zhinan Wu, Hewei Liang, Wenxi Li, Tongyuan Hu, Rui Guo, Liang Xiao, Yuanqiang Zou*, Zhigang Liu*. Synbiotics of Lactobacillus suilingensis and inulin alleviates cognitive impairment via regulating gut microbiota indole-3-lactic acid metabolism in female AD mice. Alzheimer's & Dementia. 2025. 21, 7. https://doi.org/10.1002/alz.70406. (通讯作者)
4. Mengjie Mu, Qianqian Xu, Qingyuan Hao, Xiaofang Li, Zhinan Wu, Qingfeng Zhang, Shuhan Liu, Xinai Man, Liang Xiao, Yuanqiang Zou*, Shangyong Li*, Ningning He*.Multiomics Analysis of Bacteroides cellulosilyticus Anticolitis via Gut Microbiota Metabolite-Mediated PI3K-Akt Signaling Pathway. J. Agric. Food Chem. 2025. https://doi.org/10.1021/acs.jafc.5c00637. (通讯作者)
5. Wenxi Li#, Hewei Liang#, Xiaoqian Lin#, Tongyuan Hu, Zhinan Wu, Wenxin He, Mengmeng Wang, Jiahao Zhang, Zhuye Jie, Xin Jin, Xun Xu, Jian Wang, Huanming Yang, Wenwei Zhang, Karsten Kristiansen*, Liang Xiao* & Yuanqiang Zou*. A catalog of bacterial reference genomes from cultivated human oral bacteria. npj biofilms and microbiomes. 2023. 45. (通讯作者)
6. Bei Liu, Ningning He, Hui Li, Zizhen Yang, Yichen Lin, Xiaoyu Wu, Haoyan Zhang, Ziheng Zhang, Zishuai Zhang, Yu Tian, Zhinan Wu, Yuanqiang Zou*, Jixing Peng*, Shangyong Li*. 3-Fucosyllactose Prevents Nonalcoholic Fatty Liver Disease by Modulating the Gut Microbiota-Derived Pantothenate in Mice. J. Agric. Food Chem. 2025. 73,16.DOI: 10.1021/acs.jafc.5c00079. (通讯作者)
7. Wenxin He, Hewei Liang, Wenxi Li, Xiaowei Gao, Tongyuan Hu, Xiaoqian Lin, Zhinan Wu, Jingxi Sun, Xiaofang Li, Mengmeng Wang, Xiaoxue Hou, Zhuye Jie, Xin Tong, Xin Jin, Liang Xiao & Yuanqiang Zou*. Revealing an unprecedented diversity of episymbiotic Saccharibacteria in a high-quality genome collection. npj biofilms and microbiomes. 2024. 10, 153. https://doi.org/10.1038/s41522-024-00617-2 (通讯作者)
8. Xiaoqian Lin, Tongyuan Hu, Zhinan Wu, Lingne Li, Yuhao Wang, Dingyang Wen, Xudong Liu, Wenxi Li, Hewei Liang, Xin Jin, Xun Xu, Jian Wang, Huanming Yang, Karsten Kristiansen*, Liang Xiao* & Yuanqiang Zou*. Isolation of potentially novel species expands the genomic and functional diversity of Lachnospiraceae. iMeta 2024; e174. https://doi.org/10.1002/imt2.174. (通讯作者)
9. Xiaoqian Lin, Tongyuan Hu, Jianwei Chen, Hewei Liang, Jianwei Zhou, Xin Jin, Xun Xu, Xiaohuan Jing, Jian Wang, Huanming Yang, Karsten Kristiansen*, Liang Xiao*, Yuanqiang Zou*. The genomic landscape of reference genomes of cultivated human gut bacteria. Nature Communications. 2023. 14:1663 (通讯作者)
10. Yuanqiang Zou#，Wenbin Xue#, Guangwen Luo#, Ziqing Deng#, Panpan Qin#, Ruijin Guo, Haipeng Sun, Yan Xia, Suisha Liang, Ying Dai, Daiwei Wan, Rongrong Jiang, Lili Su, Qiang Feng, Zhuye Jie, Tongkun Guo, Zhongkui Xia, Chuan Liu, Jinghong Yu, Yuxiang Lin, Shanmei Tang, Guicheng Huo, Xun Xu, Yong Hou, Xin Liu, Jian Wang, Huanming Yang, Karsten Kristiansen, Junhua Li*, Huijue Jia* & Liang Xiao*. 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses. Nature Biotechnology. 2019, 37: 179-185. （第一作者）
专利：
1.Yuanqiang Zou,… et al. Collinsella shenzhenensis and applications thereof. PCT/CN2016/109689 (First inventor)
2.Yuanqiang Zou,… et al. Lactobacillus gasseri, culture method therefor and application thereof. PCT/CN2016/111027 (First inventor)
3.Yuanqiang Zou,… et al. Anaerostipes caccae and applications thereof. PCT/CN2016/109690 (First inventor)
4.Yuanqiang Zou,… et al. Faecalibacterium butyricigenerans and method for cultivation thereof and application thereof. PCT/CN2016/094846 (First inventor)
5.Yuanqiang Zou,… et al. Faecalibacterium longum and application thereof. PCT/CN2016/098246 (First inventor)
6.Yuanqiang Zou,… et al. Christensenella intestinihominis and application thereof. PCT/CN2016/098247 (First inventor)
7.Qiang Feng, Wenbin Xue Yuanqiang Zou,… et al. Intestinal bacteria Butyribacter intestini and application thereof. PCT/CN2016/076878 (Common inventor)
Research Gate 链接：https://www.researchgate.net/profile/Yuanqiang-Zou
