修志辉(weixiaoyu@genomics.cn),博士。就职于华大股份智惠医学研究院千万微生态专项,专注于大人群队列肠道微生物宏基因组研究。通过民生项目,建立自然人群队列的肠道微生物宏基因组研究,同时,建立消化系统、糖尿病、心脑血管疾病的专病队列,研究各个疾病与肠道宏基因组的关联情况,挖掘新的检测标志物和疾病管理模型。
研究方向:肠道微生态
现任岗位:华大股份 临床科研部 专项科学家
教育背景:香港中文大学 生物学 博士
参与项目:
1.国家自然科学基金青年科学基金项目(31700210),2018.01-2020.12,结题
2.中国博士后科学基金第62批面上资助(2017M622183),2017.07-2019.09,结题
3.山东省自然科学基金博士基金(ZR2017BC084),2012.07-2018.12,结题
论文:
1.Xiu, Z.H, Sun, F., Shen, Y., Zhang, X., Jiang, R., Bonnard, G., Zhang, J.H. and Tan, B.C. (2016) EMPTY PERICARP16 is required for mitochondrial nad2 intron4 cis-splicing, complex I assembly and seed development in maize. Plant J, DOI: 10.1111/tpj.13122. IF=6.535.
2.Xiu, Z.H. #, Peng, L#., Wang, Y. #, et al (2020) Empty Pericarp24 and Empty Pericarp25 Are Required for the Splicing of Mitochondrial Introns, Complex I Assembly, and Seed Development in Maize. Front Plant Sci. DOI: 10.3389/fpls.2020.608550. IF=4.568. (共同一作)
3.Ji, Y.T. #, Xiu, Z.H. #, Chen, C.H. #, et al (2020) Long read sequencing of Toona sinensis (A. Juss) Roem: A chromosome-level reference genome for the family Meliaceae. Mol Ecol Resour. DOI: 10.1111/1755-0998.13318. IF=6.531. (共同一作)
4.Tong, Z.#, Zhou, J. #, Xiu, Z.H #, et al. (2019) Construction of a high-density genetic map with whole genome sequencing in Nicotiana tabacum L. Genomics, DOI: 10.1016/j.ygeno.2019.11.015. IF=5.222. (共同一作)
5.Tong, Z.#, Zhou, J. #, Xiu, Z.H #, et al. (2021) Quantitative trait locus mapping and genomic selection of tobacco (Nicotiana tabacum L.) based on high-density genetic map. Plant Biotech. Rep. (15): 845–854. IF=2.01. (共同一作)
6.Pang, C.Y., Bai M.Z., et al. (2019) Global transcriptome analysis of different stages of preimplantation embryo development in river buffalo. Peer J, DOI: 10.7717/peerj.8185. IF=2.457. (共同通讯作者)
7.Wei, J. #, Xiu, Z.H#, et al. (2019) Transcriptome Profile Analysis of Twisted Leaf Disease Response in Susceptible Sugarcane with Narenga porphyrocoma Genetic Background. Trop Plant Biol. DOI: 10.1007/s12042-019-09231-5. IF=1.831. (共同一作)
8.Feng, Z., Shao, D., Cai, Y., Bi, R., Ju, X., Chen, D., Song, C., Chen, X., Li, L., An, N., Li, Y., Zhou, Q., Xiu, Z.H., Zhu, S., Wu, X., & Wen, H. (2023). Homologous recombination deficiency status predicts response to platinum-based chemotherapy in Chinese patients with high-grade serous ovarian carcinoma. J Ovarian Res, 16(1), 1-11. IF=5.506.
9.Liu, H., Xiu, Z.H., Yang, H., Ma, Z., Yang, D., Wang, H., Tan, B.C. (2022) Shrek1 encodes a WD40 protein involved in ribosome biogenesis by regulating pre-rRNA processing in maize. Plant Cell, 34;4028-4044. IF=9.638.
10.Wang, Y., Li, H., Huang, Z.Q., Ma, B., Yang Y.Z., Xiu, Z.H., Wang, L., Tan, B.C. (2023) Maize PPR-E proteins mediate RNA C-to-U editing in mitochondria by recruiting the trans deaminase PCW1, Plant Cell, 35; 529–551. IF=9.638
专利:
1.一种抗肿瘤免疫细胞培养箱实用新型专利
2.一种抗肿瘤实验用肿瘤细胞培养装置实用新型专利


