吴靓（wuliang@genomics.cn），博士，研究员。主持国家自然科学青年基金1项、广东省青年基金1项、作为骨干参与国家重点研发项目1项。以第一作者或通讯作者在Cell、Cell Research和Nature Communications等杂志发表SCI文章17篇。
研究方向：基于细胞组学和时空组学的肿瘤研究及临床应用方向
现任岗位：华大研究院 主任科学家
论文:
1.Wu L#, Yan J#, Bai Y#, et al. An invasive zone in human liver cancer identified by Stereo-seq promotes hepatocyte–tumor cell crosstalk, local immunosuppression and tumor progression[J]. Cell research, 2023, 33(8): 585-603. （一作）
2.Zhu Q, Zhao X, Zhang Y, et al. Single cell multi-omics reveal intra-cell-line heterogeneity across human cancer cell lines[J]. Nature Communications, 2023, 14(1): 8170. （通讯）
3.Xiao G, Huang W, Zhong Y, et al. Uncovering the Bronchoalveolar Single-Cell Landscape of Patients With Pulmonary Tuberculosis With Human Immunodeficiency Virus Type 1 Coinfection[J]. The Journal of Infectious Diseases, 2024: jiae042. （通讯）
4.Qin P#, Chen H#, Wang Y#, et al. Cancer-associated fibroblasts undergoing neoadjuvant chemotherapy suppress rectal cancer revealed by single-cell and spatial transcriptomics[J]. Cell Reports Medicine, 2023, 4(10). （通讯）
5.Sun Y#, Wu L#*, Zhong Y#, et al. Single-cell landscape of the ecosystem in earlyrelapse hepatocellular carcinoma[J]. Cell, 2021, 184(2): 404-421. e16. （一作&通讯）
6.Wu L#*, Wang Y#, Jiang M#, et al. scDPN for High-throughput Single-cell CNV Detection to Uncover Clonal Evolution During HCC Recurrence[J]. Genomics, Proteomics & Bioinformatics, 2021. （一作&通讯）
7.Sun Y#, Wu L#, Liu S#, et al. Dissecting spatial heterogeneity and the immuneevasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma[J]. Nature communications, 2021, 12(1): 1-14. （一作）
