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张涛

张涛(tao.zhang@genomics.cn),哥本哈根大学博士,副研究员,华大学院研究生导师,深圳市人体共生微生物与健康研究重点实验室主任,《iMeta》杂志青年编委。基于基因组、宏基因组等多组学开展复杂疾病机制研究,关注心脑血管疾病、消化道肿瘤等。已发表SCI学术论文37篇,含2篇Nature Genetics 、2篇Cell Discovery、Nature Communications等,引用率超2000,H-index 17。为Nature Genetics、Nature Microbiology等国际一流杂志审稿人。申请发明专利13份,已授权10份。荣获“第二十二届专利优秀奖”,“盐田区产业人才“,“光谷3551青年人才”等称号。

研究方向:专注基因组与微生物研究,聚焦心脑血管、肿瘤等复杂疾病研究。

现任岗位:华大研究院 主任科学家

教育背景:哥本哈根大学 生物学 博士

参与项目:

1.2016YFC1303900,国家重点研发计划“慢阻肺危险因素、病因与发病机制研究”。骨干,725万

2.2023YFC2509400,国家重点研发计划”常见多发病防治研究”,子课题负责人,300万

论文:

1.Unraveling the impact of host genetics and factors on the urinary microbiome in a young population. mbio. 2024-11-8, doi.org/10.1128/mbio.02773-24

2.Integrated large-scale metagenome assembly and multi-kingdom network analyses identify sex differences in the human nasal microbiome. Genome Biology. 2024-10-08, doi.org/10.1186/s13059-024-03389-2

3.Insights into the assembly of the neovaginal microbiota in Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome patients. Nature Communications. 2024-09-08, 10.1038/s41467-024-52102-1

4.Consistent signatures in the human gut microbiome of old- and young-onset colorectal cancer. Nature Communications. 2024-04-22, 10.1038/s41467-024-47523-x

5. A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome. Communications Biology. 2024-01-30, 10.1038/s42003-024-05822-5

6.Integrated Human Skin Bacteria Genome Catalog Reveals Extensive Unexplored Habitat‐Specific Microbiome Diversity and Function. Advanced Science. 2023-08-07,10.1002/advs.202300050

7.A consortium of three-bacteria isolated from human feces inhibits formation of atherosclerotic deposits and lowers lipid levels in a mouse model. iScience. 2023-06-16, 10.1016/j.isci.2023.106960

8.Mendelian randomization analyses reveal causal relationships between the human microbiome and longevity. Scientific Reports. 2023-03-29, 10.1038/s41598-023-31115-8

9.Sex differences in the oral microbiome, host traits, and their causal relationships. iScience. 2023-01-20. 10.1016/j.isci.2022.105839

10.Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal–fetal interface. Scientific Reports. 2022-07-28, 10.1038/s41598-022-14516-z

专利:

1.miR-3977和/或miR-4693-5p的用途以及食品、药物或保健品。刘小敏、贾慧珏、张涛。CN 116999453 A

2. 类风湿性关节炎易感位点及其应用。李小苇、郭健萍、张涛、栗占国、贾慧珏。ZL201810427418.9

3.一种基于测序数据的abo血型系统分型方法及其应用。杨焕杰、马玉婷、张智霖、仝欣、张涛。ZL201810366343.8

4.二倍体基因组测序片段的单倍体分型和变异检测方法和装置。周泽、张涛。 ZL201710867439.8

5.一种与银屑病相关的分类模型的构建方法。孙良丹、张涛、甄琪、王文俊、钱文君、莫晓东、吴静、郑晓冬、李报。ZL201710692864.8

6.基于三代捕获测序对二倍体基因组单倍体分型的方法和装置。周泽、孙宇辉、张涛、章元伟。ZL201780090335.9

7.一种基于测序数据的变异检测方法、装置和存储介质。莫晓东、杨焕杰、张涛。 ZL201780089042.9

8.分型方法和装置。章元伟、张涛、曹红志。ZL201680067128.7

9.一种mhc补全数据库、其构建方法和应用。刘小敏、曹红志、刘晓、张涛。ZL201410490501.2

10.一种样本性别鉴定方法及装置。曹红志、刘爽、张涛、庄雪寒。WO 2016008146 A1

Google Scholar 链接:https://scholar.google.com/citations?hl=en&user=sUYnr3gAAAAJ 

ORCID链接:https://orcid.org/0000-0003-2765-2802 

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