邵迪(shaodi@bgi.com)。主要研究方向癌症和遗传病的多组学分子机制研究、精准预防和诊断技术开发。参与过市级重点课题2项,发表SC1论文20多篇,其中第一作者或通讯作者10篇,发明专利2项。
研究方向:精准医学,转化医学
现任岗位:临床高级科研经理
教育背景:博士 分子生物医学 丹麦哥本哈根大学
参与项目:
1.食管癌卡瑞丽珠单抗II期临床研究
2.卵巢癌HRD与铂化疗敏感性研究
3.中国遗传性肿瘤高风险人群肿瘤易感基因筛查研究
4.多组学结直肠癌早筛技术开发和组学大数据分析平台建立
论文:
1. Jun Liu†, Jingpei Li†, Wanli Lin†, Di Shao†, et al. Neoadjuvant camrelizumab plus chemotherapy for re-sectable, locally advanced oesophageal squamous cell carcinoma (NIC-ESCC2019): a multicentre, open-label, single-arm, phase 2 study. International Journal of Cancer, 2022.
2. Liu L†, Liu J†, Shao D†, et al: Comprehensive genomic profiling of lung cancer using a validated panel to explore therapeutic targets in East Asian patients. Cancer Science, 2017.
3. Shao D†, Cheng S†, Guo F†, et al. Prevalence of hereditary breast and ovarian cancer (HBOC) predisposi-tion gene mutations among 882 HBOC high-risk Chinese individuals. Cancer Science, 2020.
4. Li W†, Shao D†, Li L, et al. Germline and somatic mutations of multi-gene panel in Chinese patients with epithelial ovarian cancer: a prospective cohort study. Journal of Ovarian Research, 2019.
5. Feng Z†, Shao D†, Cai Y, et al. Homologous recombination deficiency status predicts response to plati-num-based chemotherapy in Chinese patients with high-grade serous ovarian carcinoma. Journal of Ovarian Research, 2023
专利:
1.METHOD AND DEVICE FOR GENETIC MAP CONSTRUCTION, METHOD AND DEVICE FOR HAPLOTYPEANA ANLYSIS, PCT/CN2012/080574
2.遗传图谱和单体型分析方法和装置
Research Gate 链接:
https://www.researchgate.net/profile/Di-Shao-10
ORCID 链接:
https://orcid.org/0000-0002-1485-2074


