刘龙奇(liulongqi@genomics.cn),研究员。华大集团东区首席代表、华大生命科学研究院首席科学家、中科院大学博士生导师,兼任南开大学、南方科技大学校外研究生导师。曾获广东省自然科学一等奖,深圳市优青,杭州市西湖区最美科技工作者,紫金港科技城年度生物医药领军人物。主要研究方向为时空多组学前沿技术和细胞命运调控研究。研究成果包括:作为负责人之一研发世界上首个纳米级高精度和超大视场空间组学技术 Stereo-seq并实现产业转化,系统绘制重要模式生物胚胎发育时空转录组图谱,以封面和专题文章的形式在 Cell 和 Developmental Cell 同步发表,成果入选“2022 年度中国生命科学十大进展”(Cell, 2022; Developmental Cell, 2022);首次实现在体外诱导人类全能干细胞,入选“2022 年度中国生物医药十大进展”(Nature, 2022);绘制非人灵长类细胞图谱,入选“2022 年度中国生物医药十大进展”(Nature, 2022);绘制灵长类大脑皮层(Cell, 2023)和小脑 (Science, 2024) 神经细胞空间分布图谱,相关成果入选“2023 年度中国神经科学重大进展”;作为发起人之一成立了时空组学国际联盟并在 Cell 官网发布(https://www.cell.com/consortium/spatiotemporal-omics),受邀在 Cell 杂志 50 周年专刊撰写时空组学长篇综述解析时空组学在生物学和医学领域的新机遇 (Cell, 2024)。近年来发表研究论文、评论或综述 80 余篇,申请国际发明专利 20 余项。
研究方向:细胞时空组学
现任岗位:杭州华大生命科学研究院 执行院长
教育背景:中国科学院大学 生物化学与分子生物学 博士
参与项目:
1.国家重点研发计划-前沿生物技术,高精度全景转录组深度解析技术, 2022YFC3400405, 2022/11-2027/10,在研,参与
2.科技创新 2030-“脑科学与类脑研究”重大项目:脑认知原理解析,猕猴全脑介观神经联结图谱, 2021ZD0200100, 2021/12-2026/11,在研,课题负责人
3.深圳市优秀科技创新人才培养项目, RCYX20200714114644191,非人灵长类动物单细胞染色质可及性和转录组多组学图谱构建, 2021/04/01-2024/04/01,在研,主持
4.国家自然科学基金青年科学基金, 31900466, 利用单细胞多组学测序技术鉴定人类早期胚胎核心调控因子,2020/01-2022/12,已结题,主持
5.中国博士后科学基金一等资助, 2017M610553, 单细胞染色质开放区域和转录组同时测序技术开发, 2016/8-2017/5,已结题,主持
6.国家重点基础研究发展计划(973 计划), 2011CB965200,不同组织与疾病来源的 iPS多能性差异及其调控的分子机制研究, 2011/01-2015/08,已结题, 参与
论文:
发表第一作者或通讯作者论文:
1.Xu Y, Liu L#, Laslett A L, Miguel Esteban#. Cell reprogramming: into the groove[J].Nature Materials, 2013, 12(12): 1082-1084. (#Co-corresponding authors)
2. Liu L, Xu Y, He M, et al. Transcriptional pause release is a rate-limiting step for somatic cell reprogramming[J]. Cell Stem Cell, 2014, 15(5): 574-588
Link: https://www.sciencedirect.com/science/article/pii/S1934590914004500
3. Liu L, Leng L, Liu C, et al. An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos[J]. Nat Commun 10, 364 (2019)
4. Liu L, Liu C, Quintero A, et al. Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity[J]. Nat Commun 10, 470 (2019)
5. Liu C, Wang M, Wei X, …, Liu L#. An ATAC-seq atlas of chromatin accessibility in mouse tissues[J]. Scientific data, 2019, 6(1): 1-10. (#Corresponding authors)
6. Zhu L, Yang P, Zhao Y, Zhuang Z, Wang Z, Song R, Zhang J, …, Wang F# , Gao GF#,Liu L#, Liu WJ#. (2020), Single-cell sequencing of peripheral mononuclear cells reveals distinct immune response landscapes of COVID-19 and influenza patients, Immunity,2020 Sep 15;53(3):685-696. (#Corresponding authors)
Link: https://doi.org/10.1016/j.immuni.2020.07.009
7. Mazid, M.A., Ward, C., Luo, Z., .Liu,L#., et al. Rolling back of human pluripotent stem cells to an 8-cell embryo-like stage. Nature. 2022 May;605(7909):315-324.(#Corresponding authors)
Link: https://doi.org/10.1038/s41586-022-04625-0
8. Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q,Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L,Qin B, Guo P, Lai G, Muñoz-Cánoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J,Uhlén M, Esteban MA#, Li Y#, Liu L#, Xu X#, Wang J#. Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21. (#Corresponding authors)
Link:https://doi.org/10.1016/j.cell.2022.04.003
9. Han L,Wei X, Liu C,Hou Y#,Xu X#,Esteban MA#, Liu L#. Cell transcriptomic atlas of the non-human primate Macaca fascicularis.Nature.2022 Apr;604(7907):723-731.(#Corresponding authors)
Link:https://doi.org/10.1038/s41586-022-04587-3
10. Wang M, Hu Q, Lv T,Wang Y,Lan Q,Xiang R, Tu Z,Wei Y, Han K, Shi C, Guo J, Liu C,Yang T,Du W, An Y,Cheng M, Xu J, Lu H, Li W,Zhang S, Chen A,Chen W, Li Y#,Wang X#,Xu X#,Hu Y#, Liu L#. High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae. Developmental Cell. 2022 Apr 17:S1534-5807(22)00246-5.PMID: 35512700 (#Corresponding authors)
Link:https://doi.org/10.1016/j.devcel.2022.04.006
11. Liu C, Li R, Li Y, Lin X, Zhao K, Liu Q, Wang S, Yang X, Shi X, Ma Y, Pei C, Wang H,Bao W, Hui J, Yang T, Xu Z, Lai T, Berberoglu MA, Sahu SK, Esteban MA, Ma K, Fan G, Li Y, Liu S, Chen A, Xu X#, Dong Z#, Liu L#. Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis. Developmental Cell. 2022Apr 22:S1534-5807(22)00249-0.. Online ahead of print. PMID:35512701 (#Corresponding authors)
Link:https://doi.org/10.1016/j.devcel.2022.04.009
12. Zhang X, Lai GY, Volpe G, Han L, Maxwell PH, Liu L#, Esteban MA#, Lai YW.Towards a primate single-cell atlas. Zool Res. 2022 Jul 18;43(4):691-694. doi: 10.24272/j.issn.2095-8137.2022.212. PMID: 35838039. (#Corresponding authors)
13. Liu Y*, Wang S*, Lyu M*, Xie R, Guo W, He Y, Shi X, Wang Y, Qi J, Zhu Q, Zhang H,Luo T, Chen H, Zhu Y, Dong X, Li Z, Gu Y, Liu L#, Xu X#, Liu Y#. Droplet Microfluidics Enables Tracing of Target Cells at the Single-Cell Transcriptome Resolution. Bioengineering (Basel). 2022 Nov 10;9(11):674. (#Corresponding authors)
14. Lei Y*, Cheng M*, Li Z*, Zhuang *Z, Wu L*, Sun Y*, Han L, Huang Z, Wang Y, Wang Z, Xu L, Yuan Y, Liu S, Pan T, Xie J, Liu C, Volpe G, Ward C, Lai Y, Xu J, Wang M,Yu H, Sun H, Yu Q, Wu L, Wang C, Wong CW, Liu W,Xu L, Wei J, Chen D, Shang Z,Li G, Ma K, Cheng L, Ling F, Tan T, Chen K, Tasic B, Dean M, Ji W, Yang H, Gu Y,Esteban MA, Li Y, Chen A, Niu Y#, Zeng H#, Hou Y#, Liu L#, Liu S#, Xu X#. Spatially resolved gene regulatory and disease-related vulnerability map of the adult Macaque cortex. Nature Communications. 2022 Nov 8;13(1):6747. (#Corresponding authors)
15. Shi Q, Liu S, Kristiansen K#, Liu L#. The FASTQ+ format and PISA. Bioinformatics.2022 Sep 30;38(19):4639-4642. (#Corresponding authors)
16. Chen A, Sun Y, Lei Y, Li C, Liao S, Meng J, Bai Y, Liu Z, Liang Z, Zhu Z, Yuan N, Yang H, Wu Z, Lin F, Wang K, Li M, Zhang S, Yang M, Fei T, Zhuang Z, Huang Y, Zhang Y, Xu Y, Cui L, Zhang R, Han L, Sun X, Chen B, Li W, Huangfu B, Ma K, Ma J, Li Z, Lin Y, Wang H, Zhong Y, Zhang H, Yu Q, Wang Y, Liu X, Peng J, Liu C, Chen W, Pan W, An Y, Xia S, Lu Y, Wang M, Song X, Liu S, Wang Z, Gong C, Huang X, Yuan Y, Zhao Y, Chai Q, Tan X, Liu J, Zheng M, Li S, Huang Y, Hong Y, Huang Z, Li M, Jin M, Li Y, Zhang H, Sun S, Gao L, Bai Y, Cheng M, Hu G, Liu S, Wang B, Xiang B, Li S, Li H, Chen M, Wang S, Li M, Liu W, Liu X, Zhao Q, Lisby M, Wang J, Fang J, Lin Y, Xie Q, Liu Z, He J, Xu H, Huang W, Mulder J, Yang H, Sun Y, Uhlen M, Poo M, Wang J, Yao J#, Wei W#, Li Y#, Shen Z#, Liu L#, Liu Z#, Xu X#, Li C#.Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex. Cell. 2023 July 12:S0092-8674(23)00679-7. (#Corresponding authors)
Link: https://doi.org/10.1016/j.cell.2023.06.009
发表署名作者学术论文:
1. Liao B, Bao X, Liu L, et al. MicroRNA cluster 302–367 enhances somatic cell reprogramming by accelerating a mesenchymal-to-epithelial transition[J]. Journal of Biological Chemistry, 2011, 286(19): 17359-17364.
2. Zhuang Q, Qing X, Ying Y, …, Liu L et al. Class IIa histone deacetylases and myocyte enhancer factor 2 proteins regulate the mesenchymal-to-epithelial transition of somatic cell reprogramming[J]. Journal of Biological Chemistry, 2013, 288(17): 12022-12031
3. Tian W, Wang Y, Xu Y, …, Liu L et al. The hypoxia-inducible factor renders cancer cells more sensitive to vitamin C-induced toxicity[J]. Journal of Biological Chemistry, 2014,289(6): 3339-3351
4. Wu Y, Li Y, Zhang H, …, Liu L et al. Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming[J]. Nature Cell Biology, 2015, 17(6): 715-725
5. Dong G, Shang Z, Liu L, et al. Retinoic acid combined with spermatogonial stem cell conditions facilitate the generation of mouse germ-like cells[J]. Bioscience reports, 2017,37(2)
6. Shang Z, Chen D, Wang Q, …, Liu L et al. Single-cell RNA-seq reveals dynamic transcriptome profiling in human early neural differentiation[J]. GigaScience, 2018, 7(11):giy117.
7. Fan G, Zhang Y, Liu X, …, Liu L et al. The first chromosome‐level genome for a marine mammal as a resource to study ecology and evolution[J]. Molecular Ecology Resources,2019, 19(4): 944-956.
8. He Y, Chang Y, Bao L, …, Liu L et al. A chromosome‐level genome of black rockfish,Sebastes schlegelii, provides insights into the evolution of live birth[J]. Molecular ecology resources, 2019, 19(5): 1309-1321.
9. Y, Sun N, Li C, …, Liu L, et al. Dissecting primate early post-implantation development using long-term in vitro embryo culture[J]. Science, 2019, 366(6467).
10. Zhang M, Lai Y, Krupalnik V…Liu L,et al.β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus.Science Advances. 2020 Jul 17;6(29):eaba1593.
11. Sun, Y., Yu, Q., Li, L,…, Liu L.et al. Single-cell RNA profiling links ncRNAs to spatiotemporal gene expression during C. elegans embryogenesis. Sci Rep. 2020 Nov 2;10(1):18863. doi: 10.1038/s41598-020-75801-3.PMID: 33139759
12. Li, H., Wei, X., Zhou, L. ,…, Liu L,et al. Dynamic cell transition and immune response landscapes of axolotl limb regeneration revealed by single-cell analysis. Protein Cell 12, 57–66 (2021).
13. Wang, Q., Li, J., Wang, S., Deng, Q., Wang, K., Dai, X., An, Y., Dong, G., Ke, W., Chen,F., Liu, L., Yang, H., Du, Y., Zhao, W. and Shang, Z. (2021), Single-cell transcriptome profiling reveals molecular heterogeneity in human umbilical cord tissue and cultureexpanded mesenchymal stem cells. FEBS J. 2021 Sep;288(18):5311-5330
14. Wei X, Li H, Guo Y, Zhao X, Liu Y, Zou X, Zhou L, Yuan Y, Qin Y, Mao C, Huang G, Yu Y, Deng Q, Feng W, Xu J, Wang M, Liu S, Yang H, Liu L, Liu C and Gu Y (2021) An ATAC-seq Dataset Uncovers the Regulatory Landscape During Axolotl Limb Regeneration. Front.CellDev.Biol. 2021 Mar 30;9:651145.
15. Gao S, Shi Q, Zhang Y, Liang G, Kang Z, Huang B, Ma D, Wang L, Jiao J, Fang X, Xu CR, Liu L, Xu X, Göttgens B, Li C, Liu F. Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics. Cell Res. 2022 Jan;32(1):38-53.doi: 10.1038/s41422-021-00540-7. Epub 2021 Aug 2.PMID: 34341490
16. Liu X, Jiang Y, Song D, Zhang L, Xu G, Hou R, Zhang Y, Chen J, Cheng Y, Liu L, Xu X,Chen G, Wu D, Chen T, Chen A, Wang X. Clinical challenges of tissue preparation for spatial transcriptome. Clin Transl Med. 2022 Jan;12(1):e669. doi:10.1002/ctm2.669.PMID: 35083877
17. Xiang H, Zhao Y, Li X, Liu P, Wang L, Wang M, Tian L, Sun HX, Zhang W, Xu Z, Ye B, Yuan X, Wang P, Zhang N, Gong Y, Bian C, Wang Z, Yu L, Yan J, Meng F, Bai C, Wang X, Liu X, Gao K, Wu L, Liu L, Gu Y, Bi Y, Shi Y, Zhang S, Zhu C, Xu X, Wu G, Gao GF, Yang N, Liu WJ, Yang P. Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients.Hum Immunol. 2022 Feb;83(2):119-129. doi:10.1016/j.humimm.2021.10.007. Epub 2021 Nov 4.PMID: 34785098
18. Xia K, Sun HX, Li J, Li J, Zhao Y, Chen L, Qin C, Chen R, Chen Z, Liu G, Yin R, Mu B, Wang X, Xu M, Li X, Yuan P, Qiao Y, Hao S, Wang J, Xie Q, Xu J, Liu S, Li Y, Chen A, Liu L, Yin Y, Yang H, Wang J#, Gu Y#, Xu X#. The single-cell stereo-seq reveals region-specific cell subtypes and transcriptome profiling in Arabidopsis leaves. Dev Cell. 2022 Apr 22:S1534-5807(22)00251-9. doi: 10.1016/j.devcel.2022.04.011. Online ahead of print.PMID: 35512702
19. Wang Z, Zhong Y, Zhang Z, Zhou K, Huang Z, Yu H, Liu L, Liu S, Yang H, Zhou J, Fan J, Wu L#, Sun Y#. Characteristics and Clinical Significance of T-Cell Receptor Repertoire in Hepatocellular Carcinoma. Front Immunol. 2022 Mar 16;13:847263. doi: 10.3389/fimmu.2022.847263. eCollection 2022.PMID: 35371059
20. Wang S*, Xie J*, Zou X*, Pan T, Yu Q, Zhuang Z, Zhong Y, Zhao X, Wang Z, Li R, Lei Y, Yin J, Yuan Y, Wei X, Liu L, Liu S, Yang H, Wu L#. Single-cell multiomics reveals heterogeneous cell states linked to metastatic potential in liver cancer cell lines .iScience. 2022 Feb 2;25(3):103857. doi: 10.1016/j.isci.2022.103857. eCollection 2022 Mar 18.PMID: 35198910
21. Li Y, Qi J, Liu Y, Zheng Y, Zhu H, Zang Y, Guan X, Xie S, Zhao H, Fu Y, Xiang H, Zhang W, Chen H, Liu H, Zhao Y, Feng Y, Bu F, Liang Y, Li Y, Xu Q, He Y, Sun L, Liu L, Gu Y, Xu X, Hou Y, Dong X#, Liu Y#. High-Throughput Screening of Functional NeoAntigens and Their Specific T-Cell Receptors via the Jurkat Reporter System Combined with Droplet Microfluidics. Anal Chem. 2023 Jun 27;95(25):9697-9705.
22. Wu L, Yan J, Bai Y, Chen F, Zou X, Xu J, Huang A, Hou L, Zhong Y, Jing Z, Yu Q, Zhou X, Jiang Z, Wang C, Cheng M, Ji Y, Hou Y, Luo R, Li Q, Wu L, Cheng J, Wang P, Guo D, Huang W, Lei J, Liu S, Yan Y, Chen Y, Liao S, Li Y, Sun H, Yao N, Zhang X, Zhang S, Chen X, Yu Y, Li Y, Liu F, Wang Z, Zhou S, Yang H, Yang S, Xu X, Liu L, Gao Q, Tang Z, Wang X, Wang J, Fan J, Liu S, Yang X, Chen A, Zhou J. An invasive zone in human liver cancer identified by Stereo-seq promotes hepatocyte-tumor cell crosstalk, local immunosuppression and tumor progression. Cell Research. 2023 Jun
23. Peng-Cheng Guo, Jing Zuo, Ke-Ke Huang, Guang-Yao Lai, Xiao Zhang, Juan An, Jin-Xiu Li, Li Li, Liang Wu, Yi-Ting Lin, Dong-Ye Wang, Jiang-Shan Xu, Shi-Jie Hao, Yang Wang, Rong-Hai Li, Wen Ma, Yu-Mo Song, Chang Liu, Chuan-Yu Liu, Zhen Dai, Yan Xu, Amar Deep Sharma, Michael Ott, Qing Ou-Yang, Feng Huo, Rong Fan, Yong-Yin Li,Jin-Lin Hou, Giacomo Volpe, Long-Qi Liu, Miguel A. Esteban, Yi-Wei Lai. Cell atlas ofCCl4-induced progressive liver fibrosis reveals stage-specific responses. Zoological Research, 2023, 44(3): 451-466. doi: 10.24272/j.issn.2095-8137.2023.031
24. Long Y, Ang KS, Li M, Chong KLK, Sethi R, Zhong C, Xu H, Ong Z, Sachaphibulkij K,Chen A, Zeng L, Fu H, Wu M, Lim LHK, Liu L, Chen J#. Spatially informed clustering,integration, and deconvolution of spatial transcriptomics with GraphST. Nat Commun.2023 Mar 1;14(1):1155. 01 March 2023
25. Yu H, Liu B, Zhang Y, Gao X, Wang Q, Xiang H, Peng X, Xie C, Wang Y, Hu P, Shi J, Shi Q, Zheng P, Feng C, Tang G, Liu X, Guo L, Lin X, Li J, Liu C, Huang Y, Yang N, Chen Q, Li Z, Su M, Yan Q, Pei R, Chen X, Liu L, Hu F, Liang D, Ke B, Ke C#, Li F#, He J#, Wang M#, Chen L#, Xiong X#, Tang X#. Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants. Nat Commun. 2023 Feb 24;14(1):1058.
26. ang S, Chen B, Zhang Y, Sun H, Liu L, Liu S, Li Y#, Xu X#. Computational Approaches and Challenges in Spatial Transcriptomics. Genomics Proteomics Bioinformatics. 2023 Feb;21(1):24-47.
27. Yin J*, Zhao Y*, Huang F*, Yang Y*, Huang Y*, Zhuang Z*, Wang Y*, Wang Z, Lin X, Zheng Y, Zhou W, Wang S, Xu Z, Ye B, Guo Y, Lei W, Li L, Tian J, Gan J, Wang H, Wang W, Ma P, Liu C, Wei X, Shi X, Wang Z, Wang Y, Liu Y, Yang M, Yuan Y, Song Y, Ma W, Huang Z, Liu Y, Huang Y, Lu H, Liu P, Liang H, Hou Y, Xu X, Liu L, Zhang Y#, Wu G#, Gao GF#, Jin X#, Liu C#, Yang X#, Liu WJ#. Immune response and homeostasis mechanism following administration of BBIBP-CorV SARS-CoV-2 inactivated vaccine. Innovation (Camb). 2023 Jan 30;4(1):100359.
28. Xie R, Liu Y, Wang S, Shi X, Zhao Z, Liu L, Liu Y#, Li Z#. Combinatorial perturbation sequencing on single cells using microwell-based droplet random pairing. Biosens Bioelectron. 2023 Jan 15;220:114913.
29. Dai X*, Shao H, Sun N, Ci B, Wu J, Liu C, Wu L, Yuan Y, Wei X, Yang H, Liu L, Ji W, Bai B, Shang Z#, Tan T#. Developmental dynamics of chromatin accessibility during postimplantation development of monkey embryos. Gigascience. 2022 Dec 28;12:giad038.
30. Shi X*, Zhuang Y*, Chen Z*, Xu M, Kuang J, Sun XL, Gao L, Kuang X, Zhang H, Li W, Wong SZH, Liu C, Liu L, Jiang D, Pei D, Lin Y#, Wu QF#. Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset. Science Advances. 2022 Nov 18;8(46):eabq2987.
31. Wei X*, Fu S*, Li H*, Liu Y*, Wang S*, Feng W*, Yang Y*, Liu X, Zeng YY, Cheng M, Lai Y, Qiu X, Wu L, Zhang N, Jiang Y, Xu J, Su X, Peng C, Han L, Lou WP, Liu C, Yuan Y, Ma K, Yang T, Pan X, Gao S, Chen A, Esteban MA, Yang H, Wang J, Fan G, Liu L, Chen L#, Xu X#, Fei J#F, Gu Y#. Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration. Science. 2022 Sep 2;377(6610):eabp9444.
32. Li Q*, Wang M*, Zhang P*, Liu Y*, Guo Q, Zhu Y, Wen T, Dai X, Zhang X, Nagel M, Dethlefsen BH, Xie N, Zhao J, Jiang W, Han L, Wu L, Zhong W, Wang Z, Wei X, Dai W, Liu L, Xu X, Lu H, Yang H, Wang J, Boomsma JJ, Liu C#, Zhang G#, Liu W#. A singlecell transcriptomic atlas tracking the neural basis of division of labour in an ant superorganism. Nature Ecology Evolution.2022 Aug;6(8):1191-1204.
33. Guo Q*, Zhong Y*, Wang Z*, Cao T*, Zhang M, Zhang P, Huang W, Bi J, Yuan Y, Ou M, Zou X, Xiao G, Yang Y, Liu S, Liu L, Wang Z, Zhang G#, Wu L#. Single-cell transcriptomic landscape identifies the expansion of peripheral blood monocytes as an indicator of HIV-1-TB co-infection. Cell Insight. 2022 Jan 21;1(1):100005.


