李月娇（liyuejiao@genomics.cn）。清华大学，博士后。深圳华大生命科学研究院，生物技术副研究员。深圳市海外高层次人才（孔雀C类）-2021年。深圳市盐田区梧桐人才（C级）-2021年。项目组基于华大自主研发的单细胞转录组、空间转录组等技术，绘制人类早期胚胎发育的组织器官图谱，揭示器官行成过程中的转录调控机制，并进一步描绘重大出生缺陷和发育异常的单细胞时空图谱，解析胚胎发育异常的关键机制。
研究方向：胚胎发育的多组学研究
现任岗位：华大研究院-精准健康研究所生物技术副研究员
教育背景：香港中文大学生物医学博士
参与项目:
1.重大出生缺陷和发育异常突变体时空组
2.胚胎发育的时空转录组研究
3.21三体胎儿组织器官图谱
4.类胚胎时空转录组研究
5.空间转录组揭示间充质干细胞来源的小细胞外囊泡治疗卵巢早衰的机制
论文:
1. Yuejiao Li†; Tao Yang†; Tingting Lai†; Lijin You†; Fan Yang†; Jiaying Qiu†; Lina Wang; Wensi Du; Cong Hua; Zhicheng Xu; Jia Cai; Zhiyong Li; Yiqun Liu; Ling Li; Minwen Zhang; Jing Chen; Lei Zhang; Dongsheng Chen; Weiwen Wang; Shiping Liu; Liang Wu; Wenjun Zeng; Bo Wang; Xiaofeng Wei; Long qi Liu; Fengzhen Chen; CDCP: a visualization and analyzing platform for single-cell datasets, Journal of Genetics and Genomics, 2021, 21: S1673-8527
2. Yuejiao Li†; Dong, Yankai†; Ran, Ye†; Zhang, Yanan; Wu, Boyao; Xie, Jundong; Cao, Yanpei; Mo, Miaohua; Li, Sen; Deng, Hao; Hao, Wenbo; Yu, Shengyuan; Wu, Yaojiong; Three-dimensional cultured mesenchymal stem cells enhance repair of ischemic stroke through inhibition of microglia, Stem Cell Research & Therapy, 2021, 12(1): 0-358
3.Dongsheng Chen†,*, Zhihua Ou†, Jiacheng Zhu†, Haoyu Wang†, Peiwen Ding†, Lihua Luo†, Xiangning Ding, Chengcheng Sun, Tianming Lan, Sunil Kumar Sahu, Weiying Wu, Yuting Yuan, Wendi Wu, Jiaying Qiu, Yixin Zhu, Qizhen Yue, Yi Jia, Yanan Wei, Qiuyu Qin, Runchu Li, Wandong Zhao, Zhiyuan Lv, Mingyi Pu, Boqiong Lv, Shangchen Yang, Ashley Chang, Xiaofeng Wei, Fengzhen Chen, Tao Yang, Zhenyong Wei, Fan Yang, Peijing Zhang, Guoji Guo, Yuejiao Li*, Yan Hua*, Huan Liu*; Screening of cell-virus, cell-cell, gene-gene cross-talks among kingdoms of life at single cell resolution, Clinical and Translational Medicine, 2022, 12(8):e886
4. Ye Ran†, Yankai Dong†, Yuejiao Li†, Jundong Xie, Shubin Zeng, Chuanlei Liang, Wei Dai, Wenjing Tang, Yaojiong Wu, Shengyuan Yu; Mesenchymal stem cell aggregation mediated by integrin α4/VCAM-1 after intrathecal transplantation in MCAO rats, Stem Cell Research & Therapy, 2022, 13(1):507
5.Yang Wang; Yuejiao Li; Chen Guo; Qin Lu; Weiping Wang; Zhuqing Jia; Ping Chen; Kangtao Ma; Danny Reinberg; Chunyan Zhou ; ISL1 and JMJD3 synergistically control cardiac differentiation of embryonic stem cells, Nucleic Acid Research, 2016, 44(14): 6741-6755
6. Dongsheng Chen*,†, Cong Tan†, Peiwen Ding†, Lihua Luo†, Jiacheng Zhu†,Xiaosen Jiang†, Zhihua Ou, Xiangning Ding, Tianming Lan, Yixin Zhu, Yi Jia,Yanan Wei, Runchu Li, Qiuyu Qin, Chengcheng Sun, Wandong Zhao, Zhiyuan Lv, Haoyu Wang, Wendi Wu, Yuting Yuan, Mingyi Pu, Yuejiao Li, Yanan Zhang, Ashley Chang, Guoji Guo, Yong Bai*, Xin Jin*, and Huan Liu*; VThunter: a database for single-cell screening of virus target cells in the animal kingdom, Nucleic Acids Res, 2022, 50(D1): D934-D942
7.Zhibin Li†, Chengcheng Sun†, Fei Wang†, Xiran Wang†, Jiacheng Zhu, Lihua Luo, Xiangning Ding, Yanan Zhang, Peiwen Ding, Haoyu Wang, Mingyi Pu, Yuejiao Li, Shiyou Wang, Qiuyu Qin, Yanan Wei, Jian Sun, Xiangdong Wang*, Yonglun Luo*, Dongsheng Chen*, Wei Qiu*; Molecular mechanisms governing circulating immune cell heterogeneity across different species revealed by single-cell sequencing, Clinical and Translational Medicine, 2022, 12(1):e689
