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李艳

李艳(liyan@genomics.cn)。深圳华大生命科学研究院专项科学家。获得荣誉:1.Open Science Excellent Author Program,Wiley,Corresponding author 2.Best Short Talk Award,World Forum for Spine Research 2014,Individual award 3.HPC Innovation Excellence Award,International Data Corporation,Group award/key contributor 4.2021 Best Practice Awards,Bio-It World,Group award/key contributor

研究方向:复杂性状和疾病的遗传背景解析

现任岗位:华大研究院-精准健康研究所专项科学家,

教育背景:香港大学统计遗传学博士

参与项目:

1. 中国人群多组学健康评估系统构建

2. 基于多源大数据的健康长寿关键影响因素研究

3. 国别基因组计划

论文:

1.  Nie, Chao, Yan Li, Rui Li, Yizhen Yan, Detao Zhang, Tao Li, Zhiming Li et al. "Distinct biological ages of organs and systems identified from a multi-omics study." Cell reports 38, no. 10 (2022).

2.  Hu, Dingxue, Yan Li, Detao Zhang, Jiahong Ding, Zijun Song, Junxia Min, Yi Zeng, and Chao Nie. "Genetic trade‐offs between complex diseases and longevity." Aging Cell 21, no. 7 (2022): e13654.

3. Szpak, Michał, Stephan C. Collins, Yan Li, Xiao Liu, Qasim Ayub, Marie-Christine Fischer, Valerie E. Vancollie et al. "A Positively selected MAGEE2 LoF allele is associated with sexual dimorphism in human brain size and shows similar phenotypes in Magee2 null mice." Molecular biology and evolution 38, no. 12 (2021): 5655-5663.

4.  Li, Yan, Dino Samartzis, Desmond D. Campbell, Stacey S. Cherny, Kenneth MC Cheung, Keith DK Luk, Jaro Karppinen et al. "Two subtypes of intervertebral disc degeneration distinguished by large-scale population-based study." The Spine Journal 16, no. 9 (2016): 1

5.  Zhang Wei, Wan Ziyun, Li Xiaoyu, Li Rui, Luo Lihua, Song Zijun, Miao Y, Li Z, Wang S, Shan Ying, Li Yan. A population-based study of precision health assessments using multi-omics network-derived biological functional modules. Cell Reports Medicine. 2022 Dec 20;3(12).

书籍: 

Kenneth M.C. Cheung, Yan Li, Danny Chan, Pak Sham, Genetics of Lumbar Disc Degeneration, Advanced Concepts in Lumbar Degenerative Disk Disease, Springer, DOI 10.1007/978-3-662-47756-4

软著:

华大家人app, 多组学数据报告展示平台,贝类遗传育种评估系统




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